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Semaphorin 3A Signaling Through Neuropilin-1 Is an Early Trigger for Distal Axonopathy in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive distal axonopathy that precedes actual motor neuron death. Triggers for neuromuscular junction degeneration remain to be determined, but the axon repulsion factor semaphorin 3A (Sema3A), which is derived from...

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Библиографические подробности
Главные авторы: Venkova, Kalina, Christov, Alexander, Kamaluddin, Zarine, Kobalka, Peter, Siddiqui, Saaid, Hensley, Kenneth
Формат: Artigo
Язык:Inglês
Опубликовано: American Association of Neuropathologists 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072440/
https://ncbi.nlm.nih.gov/pubmed/24918638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000086
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