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Involvement of Matrix Metalloproteinase-9 in Amyloid-β 1–42–Induced Shedding of the Pericyte Proteoglycan NG2

Deposition of amyloid-β (Aβ) 1–42, the major component of senile plaques characteristic of Alzheimer disease, affects brain microvascular integrity and causes blood-brain barrier dysfunction, increased angiogenesis, and pericyte degeneration. To understand the cellular events underlying Aβ1–42 effec...

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Detalhes bibliográficos
Main Authors: Schultz, Nina, Nielsen, Henrietta M., Minthon, Lennart, Wennström, Malin
Formato: Artigo
Idioma:Inglês
Publicado em: American Association of Neuropathologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072439/
https://ncbi.nlm.nih.gov/pubmed/24918635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000084
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