LGR5 is required for the maintenance of spheroid-derived colon cancer stem cells

Colon cancer stem cells (CCSCs) are involved in colon cancer and promote tumor progression and recurrence. LGR5, a marker for intestinal stem cells (ISCs), is also considered to serve as a marker for CCSCs. However, the precise function of LGR5 in CCSCs is unclear. In this study, we demonstrated tha...

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Bibliografiske detaljer
Main Authors: CHEN, XIANG, WEI, BO, HAN, XIAOYAN, ZHENG, ZONGHENG, HUANG, JIANGLONG, LIU, JIANPEI, HUANG, YONG, WEI, HONGBO
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072401/
https://ncbi.nlm.nih.gov/pubmed/24789370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2014.1752
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