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Protection of Guinea Pigs against Leptospira interrogans Serovar Lai by LipL21 DNA Vaccine
In this study, the full lipL21 gene fragment encoding outer membrane protein LipL21 was cloned from L. interrogans serovar Lai and inserted into eukaryotic expression vector pcDNA3.1(+). The guinea pigs were immunized with pcDNA3.1(+)-lipL21, pcDNA3.1(+) or PBS. Six weeks after the second immunizati...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4072393/ https://ncbi.nlm.nih.gov/pubmed/18954563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2008.48 |
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