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Ketoconazole Inhibits Ovulation as a Result of Arrest of Follicular Steroidogenesis in the Rat Ovary

OBJECTIVE: Ketoconazole (KCZ) is a known inhibitor of steroidogenic P450 enzymes in the adrenal cortex and the gonads. Previous studies examined the potential clinical use of KCZ for attenuation of ovarian response to gonadotropin treatments. This study aimed to use the superovuating rat model to ex...

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Detalhes bibliográficos
Main Authors: Gal, Michael, Orly, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071760/
https://ncbi.nlm.nih.gov/pubmed/24987273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMRH.S15887
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