MHC class-I associated phosphopeptides are the targets of memory-like immunity in leukemia

Deregulation of signaling pathways involving phosphorylation is a hallmark of malignant transformation. Degradation of phosphoproteins generates cancer-specific phosphopeptides that are associated with MHC-I and II molecules and recognized by T-cells. We identified 95 phosphopeptides presented on th...

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Detalhes bibliográficos
Main Authors: Cobbold, Mark, De La Peña, Hugo, Norris, Andrew, Polefrone, Joy, Qian, Jie, English, A. Michelle, Cummings, Kara, Penny, Sarah, Turner, James E., Cottine, Jennifer, Abelin, Jennifer G, Malaker, Stacy A, Zarling, Angela L, Huang, Hsing-Wen, Goodyear, Oliver, Freeman, Sylvie, Shabanowitz, Jeffrey, Pratt, Guy, Craddock, Charles, Williams, Michael E, Hunt, Donald F, Engelhard, Victor H
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071620/
https://ncbi.nlm.nih.gov/pubmed/24048523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006061
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