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Chromomycins A(2) and A(3) from Marine Actinomycetes with TRAIL Resistance-Overcoming and Wnt Signal Inhibitory Activities

A biological screening study of an actinomycetes strain assembly was conducted using a cell-based cytotoxicity assay. The CKK1019 strain was isolated from a sea sand sample. Cytotoxicity-guided fractionation of the CKK1019 strain culture broth, which exhibited cytotoxicity, led to the isolation of c...

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Autori principali: Toume, Kazufumi, Tsukahara, Kentaro, Ito, Hanako, Arai, Midori A., Ishibashi, Masami
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071586/
https://ncbi.nlm.nih.gov/pubmed/24905484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12063466
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