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Local delivery of recombinant human bone morphogenetic proteins and bisphosphonate via sucrose acetate isobutyrate can prevent femoral head collapse in Legg-Calve-Perthes disease: a pilot study in pigs

PURPOSE: Legg-Calve-Perthes disease is a paediatric condition encompassing idiopathic osteonecrosis of the femoral head (ONFH). Preventing collapse and the need for subsequent joint replacement remains the major goal of clinical management. This exploratory study utilises a porcine model of surgical...

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Detalhes bibliográficos
Main Authors: Cheng, Tegan L., Murphy, Ciara M., Cantrill, Laurence C., Mikulec, Kathy, Carpenter, Clare, Schindeler, Aaron, Little, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071497/
https://ncbi.nlm.nih.gov/pubmed/24389948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00264-013-2255-0
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