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Stromal heparan sulfate differentiates neuroblasts to suppress neuroblastoma growth

Neuroblastoma prognosis is dependent on both the differentiation state and stromal content of the tumor. Neuroblastoma tumor stroma is thought to suppress neuroblast growth via release of soluble differentiating factors. Here, we identified critical growth-limiting components of the differentiating...

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Detalhes bibliográficos
Main Authors: Knelson, Erik H., Gaviglio, Angela L., Nee, Jasmine C., Starr, Mark D., Nixon, Andrew B., Marcus, Stephen G., Blobe, Gerard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071405/
https://ncbi.nlm.nih.gov/pubmed/24937430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74270
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