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Targeted therapy for cancer: the GIST model
GISTs are unique tumors that arise largely due to oncogenic mutations in KIT or PDGFRA tyrosine kinases. Although surgery remains the most effective treatment, the remarkable clinical success achieved with kinase inhibition in both the adjuvant and metastatic settings has made GIST one of the most s...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4071221/ https://ncbi.nlm.nih.gov/pubmed/24012400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.soc.2013.06.001 |
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