METHAMPHETAMINE-INDUCED NEUROTOXICITY DISRUPTS PHARMACOLOGICALLY EVOKED DOPAMINE TRANSIENTS IN THE DORSOMEDIAL AND DORSOLATERAL STRIATUM

Phasic dopamine (DA) signaling, during which burst firing by dopamine neurons generates short-lived elevations in extracellular DA in terminal fields called DA transients, is implicated in reinforcement learning. Disrupted phasic DA signaling is proposed to link DA depletions and cognitive-behaviora...

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Main Authors: Robinson, John D., Howard, Christopher D., Pastuzyn, Elissa D., Byers, Diane L., Keefe, Kristen A., Garris, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071119/
https://ncbi.nlm.nih.gov/pubmed/24562969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-014-9459-y
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