pH-Sensitive Nanomicelles for Controlled and Efficient Drug Delivery to Human Colorectal Carcinoma LoVo Cells

BACKGROUND: The triblock copolymers PEG-P(Asp-DIP)-P(Lys-Ca) (PEALCa) of polyethylene glycol (PEG), poly(N-(N’,N’-diisopropylaminoethyl) aspartamide) (P(Asp-DIP)), and poly (lysine-cholic acid) (P(Lys-Ca)) were synthesized as a pH-sensitive drug delivery system. In neutral aqueous environment such a...

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Hlavní autoři: Feng, Shi-Ting, Li, Jingguo, Luo, Yanji, Yin, Tinghui, Cai, Huasong, Wang, Yong, Dong, Zhi, Shuai, Xintao, Li, Zi-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071001/
https://ncbi.nlm.nih.gov/pubmed/24964012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100732
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