Caffeic Acid Phenethylester Increases Stress Resistance and Enhances Lifespan in Caenorhabditis elegans by Modulation of the Insulin-Like DAF-16 Signalling Pathway

CAPE is an active constituent of propolis which is widely used in traditional medicine. This hydroxycinnamic acid derivate is a known activator of the redox-active Nrf2 signalling pathway in mammalian cells. We used C. elegans to investigate the effects of this compound on accumulation of reactive o...

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Bibliographic Details
Main Authors: Havermann, Susannah, Chovolou, Yvonni, Humpf, Hans-Ulrich, Wätjen, Wim
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070918/
https://ncbi.nlm.nih.gov/pubmed/24964141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100256
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