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P38 MAPK signaling underlies a cell autonomous loss of stem cell self-renewal in aged skeletal muscle
Skeletal muscle aging results in a gradual loss of skeletal muscle mass, skeletal muscle function and decreased regenerative capacity, which can lead to sarcopenia and increased mortality. While the mechanisms underlying sarcopenia remain unclear, the skeletal muscle stem cell, or satellite cell, is...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070883/ https://ncbi.nlm.nih.gov/pubmed/24531379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3465 |
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