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Analysis of Multiple Positive Feedback Paradigms Demonstrates a Complete Absence of LH Surges and GnRH Activation in Mice Lacking Kisspeptin Signaling

Kisspeptin stimulates gonadotropin-releasing hormone (GnRH) neurons via the kisspeptin receptor, Kiss1r. In rodents, estrogen-responsive kisspeptin neurons in the rostral hypothalamus have been postulated to mediate estrogen-induced positive feedback induction of the preovulatory luteinizing hormone...

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Autores principales: Dror, Tal, Franks, Jennifer, Kauffman, Alexander S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for the Study of Reproduction, Inc. 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070868/
https://ncbi.nlm.nih.gov/pubmed/23595904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.113.108555
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