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The genetic basis of ankylosing spondylitis: new insights into disease pathogenesis

Ankylosing spondylitis (AS) is a complex disease involving multiple risk factors, both genetic and environmental. AS patients are predominantly young men, and the disease is characterized by inflammation and ankylosis, mainly at the cartilage–bone interface and enthesis. HLA-B27 has been known to be...

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Detalhes bibliográficos
Main Authors: Tsui, Florence WL, Tsui, Hing Wo, Akram, Ali, Haroon, Nigil, Inman, Robert D
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070859/
https://ncbi.nlm.nih.gov/pubmed/24971029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S37325
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