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Patterns of sequencing coverage bias revealed by ultra-deep sequencing of vertebrate mitochondria
BACKGROUND: Genome and transcriptome sequencing applications that rely on variation in sequence depth can be negatively affected if there are systematic biases in coverage. We have investigated patterns of local variation in sequencing coverage by utilising ultra-deep sequencing (>100,000X) of mt...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070552/ https://ncbi.nlm.nih.gov/pubmed/24923674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-467 |
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