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Patterns of sequencing coverage bias revealed by ultra-deep sequencing of vertebrate mitochondria

BACKGROUND: Genome and transcriptome sequencing applications that rely on variation in sequence depth can be negatively affected if there are systematic biases in coverage. We have investigated patterns of local variation in sequencing coverage by utilising ultra-deep sequencing (>100,000X) of mt...

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Detalhes bibliográficos
Main Authors: Ekblom, Robert, Smeds, Linnéa, Ellegren, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070552/
https://ncbi.nlm.nih.gov/pubmed/24923674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-467
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