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Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing
Current drug-safety assays for hepatotoxicity rely on biomarkers with low predictive power. The production of radical species, specifically reactive oxygen species (ROS) and reactive nitrogen species (RNS), has been proposed as an early unifying event linking the bioactivation of drugs to hepatotoxi...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070437/ https://ncbi.nlm.nih.gov/pubmed/24658645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2838 |
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