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Frequent red cell transfusions reduced vascular endothelial activation and thrombogenicity in children with sickle cell anemia and high stroke risk

Stroke is one of the most disabling complications of sickle cell anemia (SCA). The molecular mechanisms leading to stroke in SCA or by which packed red blood cell (PRBC) transfusion prevents strokes are not understood. We investigated the effects of PRBC transfusion on serum biomarkers in children w...

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Bibliographic Details
Main Authors: Hyacinth, Hyacinth I., Adams, Robert J., Voeks, Jenifer H., Hibbert, Jacqueline M., Gee, Beatrice E.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070426/
https://ncbi.nlm.nih.gov/pubmed/23996496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23586
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