Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis

BACKGROUND: Effective therapies for early endometrial cancer usually involve surgical excision and consequent infertility Therefore, new treatment approaches that preserve fertility should be developed. Metformin, a well-tolerated anti-diabetic drug, can inhibit cancer cell growth. However, the mech...

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Detalhes bibliográficos
Main Authors: Takahashi, Akimasa, Kimura, Fuminori, Yamanaka, Akiyoshi, Takebayashi, Akie, Kita, Nobuyuki, Takahashi, Kentaro, Murakami, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070401/
https://ncbi.nlm.nih.gov/pubmed/24966801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-14-53
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