GNAS Gene Variants Affect β-blocker–related Survival after Coronary Artery Bypass Grafting

BACKGROUND: Cardiac overexpression of the β-adrenoreceptor (βAR)–coupled stimulatory G-protein subunit Gαs enhances inotropic responses to adrenergic stimulation and improves survival in mice under βAR blockade. The authors recently identified three common haplotypes in the GNAS gene encoding Gαs, w...

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Main Authors: Frey, Ulrich H., Muehlschlegel, Jochen D., Ochterbeck, Christoph, Fox, Amanda A., Shernan, Stanton K., Collard, Charles D., Lichtner, Peter, Peters, Jürgen, Body, Simon
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070180/
https://ncbi.nlm.nih.gov/pubmed/24755784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000189
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