GNAS Gene Variants Affect β-blocker–related Survival after Coronary Artery Bypass Grafting

BACKGROUND: Cardiac overexpression of the β-adrenoreceptor (βAR)–coupled stimulatory G-protein subunit Gαs enhances inotropic responses to adrenergic stimulation and improves survival in mice under βAR blockade. The authors recently identified three common haplotypes in the GNAS gene encoding Gαs, w...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Frey, Ulrich H., Muehlschlegel, Jochen D., Ochterbeck, Christoph, Fox, Amanda A., Shernan, Stanton K., Collard, Charles D., Lichtner, Peter, Peters, Jürgen, Body, Simon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070180/
https://ncbi.nlm.nih.gov/pubmed/24755784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000189
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