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An extensive analysis of disease-gene associations using network integration and fast kernel-based gene prioritization methods

OBJECTIVE: In the context of “network medicine”, gene prioritization methods represent one of the main tools to discover candidate disease genes by exploiting the large amount of data covering different types of functional relationships between genes. Several works proposed to integrate multiple sou...

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Main Authors: Valentini, Giorgio, Paccanaro, Alberto, Caniza, Horacio, Romero, Alfonso E., Re, Matteo
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Science Publishing 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070077/
https://ncbi.nlm.nih.gov/pubmed/24726035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.artmed.2014.03.003
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