Molecular docking studies of benzimidazopyrimidine and coumarin substituted benzimidazopyrimidine derivatives: As potential human Aurora A kinase inhibitors

Protein kinases are important drug targets in human cancers, inflammation and metabolic diseases. Docking studies was performed for all the benzimidazopyrimidine and coumarin substituted benzimidazopyridimine derivatives with human Aurora A kinase target (3FDN) employing flexible ligand docking appr...

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Detalhes bibliográficos
Main Authors: Chandra, Puttaraju, Kallimeledoddi B, Mahesh, Sankanahally Srinivasshetty, Shivashankar, Kalegowda, Lokanath, Neratur Krishnappagowda, Madegowda, Mahendra
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2014
Assuntos:
Hypothesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070038/
https://ncbi.nlm.nih.gov/pubmed/24966536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010288
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