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DCC is expressed in a CD166-positive subpopulation of chondrocytes in human osteoarthritic cartilage and modulates CRE activity

Objective: In a recent study we determined a strong differential expression of DCC in OA compared to normal chondrocytes and a strong impact of the DCC receptor on cellular mobility triggered by its ligand Netrin-1. Migration of chondrocytes or their progenitor cells may play a role in remodeling of...

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Détails bibliographiques
Auteurs principaux: Bosserhoff, Anja-Katrin, Hofmeister, Simone, Ruedel, Anke, Schubert, Thomas
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069887/
https://ncbi.nlm.nih.gov/pubmed/24966904
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