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Age-related changes in tissue macrophages precede cardiac functional impairment

Cardiac tissue macrophages (cTMs) are abundant in the murine heart but the extent to which the cTM phenotype changes with age is unknown. This study characterizes aging-dependent phenotypic changes in cTM subsets. Using the Cx(3)cr1(GFP/+) mouse reporter line where GFP marks cTMs, and the tissue mac...

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Detalhes bibliográficos
Main Authors: Pinto, Alexander R., Godwin, James W., Chandran, Anjana, Hersey, Lucy, Ilinykh, Alexei, Debuque, Ryan, Wang, Lina, Rosenthal, Nadia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069267/
https://ncbi.nlm.nih.gov/pubmed/24861132
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