Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell ALL

BACKGROUND: Hispanic children have a higher incidence of acute lymphoblastic leukemia (ALL) than non-Hispanic whites, but tend to be diagnosed at older ages. In genome-wide association studies, Native American ancestry and polymorphisms in six genes have been associated with ALL risk. METHODS: In mu...

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Main Authors: Walsh, Kyle M., de Smith, Adam J., Welch, Tara C., Smirnov, Ivan, Cunningham, Marc J., Ma, Xiaomei, Chokkalingam, Anand P., Dahl, Gary V., Roberts, William, Barcellos, Lisa F., Buffler, Patricia A., Metayer, Catherine, Wiemels, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069235/
https://ncbi.nlm.nih.gov/pubmed/24753091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23727
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