Development to Term of Cloned Cattle Derived from Donor Cells Treated with Valproic Acid

Cloning of mammals by somatic cell nuclear transfer (SCNT) is still plagued by low efficiency. The epigenetic modifications established during cellular differentiation are a major factor determining this low efficiency as they act as epigenetic barriers restricting reprogramming of somatic nuclei. I...

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Autori principali: Sangalli, Juliano Rodrigues, Chiaratti, Marcos Roberto, De Bem, Tiago Henrique Camara, de Araújo, Reno Roldi, Bressan, Fabiana Fernandes, Sampaio, Rafael Vilar, Perecin, Felipe, Smith, Lawrence Charles, King, Willian Allan, Meirelles, Flávio Vieira
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069182/
https://ncbi.nlm.nih.gov/pubmed/24959750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101022
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