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Spinal SIRT1 Activation Attenuates Neuropathic Pain in Mice
Abnormal histone acetylation occurs during neuropathic pain through an epigenetic mechanism. Silent information regulator 1 (sir2 or SIRT1), a NAD-dependent deacetylase, plays complex systemic roles in a variety of processes through deacetylating acetylated histone and other specific substrates. But...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4069177/ https://ncbi.nlm.nih.gov/pubmed/24959710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100938 |
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