Spinal SIRT1 Activation Attenuates Neuropathic Pain in Mice

Abnormal histone acetylation occurs during neuropathic pain through an epigenetic mechanism. Silent information regulator 1 (sir2 or SIRT1), a NAD-dependent deacetylase, plays complex systemic roles in a variety of processes through deacetylating acetylated histone and other specific substrates. But...

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Detalhes bibliográficos
Main Authors: Shao, Haijun, Xue, Qingsheng, Zhang, Fujun, Luo, Yan, Zhu, Hao, Zhang, Xiaoqing, Zhang, Honghai, Ding, Wenlong, Yu, Buwei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069177/
https://ncbi.nlm.nih.gov/pubmed/24959710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100938
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