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Cooperation of Tyrosine Kinase Receptor TrkB and Epidermal Growth Factor Receptor Signaling Enhances Migration and Dispersal of Lung Tumor Cells

TrkB mediates the effects of brain-derived neurotrophic factor (BDNF) in neuronal and nonnneuronal cells. Based on recent reports that TrkB can also be transactivated through epidermal growth-factor receptor (EGFR) signaling and thus regulates migration of early neurons, we investigated the role of...

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Bibliographic Details
Main Authors: Götz, Rudolf, Sendtner, Michael
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069166/
https://ncbi.nlm.nih.gov/pubmed/24959744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100944
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