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Anti-Hypotensive Treatment and Endothelin Blockade Synergistically Antagonize Exercise Fatigue in Rats under Simulated High Altitude

Rapid ascent to high altitude causes illness and fatigue, and there is a demand for effective acute treatments to alleviate such effects. We hypothesized that increased oxygen delivery to the tissue using a combination of a hypertensive agent and an endothelin receptor A antagonist drugs would limit...

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Hlavní autoři: Radiloff, Daniel, Zhao, Yulin, Boico, Alina, Blueschke, Gert, Palmer, Gregory, Fontanella, Andrew, Dewhirst, Mark, Piantadosi, Claude A., Noveck, Robert, Irwin, David, Hamilton, Karyn, Klitzman, Bruce, Schroeder, Thies
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068990/
https://ncbi.nlm.nih.gov/pubmed/24960187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099309
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