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Distinct functions of the laminin β LN domain and collagen IV during cardiac extracellular matrix formation and stabilization of alary muscle attachments revealed by EMS mutagenesis in Drosophila

BACKGROUND: The Drosophila heart (dorsal vessel) is a relatively simple tubular organ that serves as a model for several aspects of cardiogenesis. Cardiac morphogenesis, proper heart function and stability require structural components whose identity and ways of assembly are only partially understoo...

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Detalhes bibliográficos
Main Authors: Hollfelder, Dominik, Frasch, Manfred, Reim, Ingolf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068974/
https://ncbi.nlm.nih.gov/pubmed/24935095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-14-26
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