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Cigarette Smoke Activates the Proto-Oncogene c-Src to Promote Airway Inflammation and Lung Tissue Destruction

The diagnosis of chronic obstructive pulmonary disease (COPD) confers a 2-fold increased lung cancer risk even after adjusting for cigarette smoking, suggesting that common pathways are operative in both diseases. Although the role of the tyrosine kinase c-Src is established in lung cancer, less is...

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Autors principals: Geraghty, Patrick, Hardigan, Andrew, Foronjy, Robert F.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068937/
https://ncbi.nlm.nih.gov/pubmed/24111605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0258OC
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