Dysregulation of Galectin-3. Implications for Hermansky-Pudlak Syndrome Pulmonary Fibrosis

The etiology of Hermansky-Pudlak syndrome (HPS) pulmonary fibrosis (HPSPF), a progressive interstitial lung disease with high mortality, is unknown. Galectin-3 is a β-galactoside–binding lectin with profibrotic effects. The objective of this study was to investigate the involvement of galectin-3 in...

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Main Authors: Cullinane, Andrew R., Yeager, Caroline, Dorward, Heidi, Carmona-Rivera, Carmelo, Wu, Hai Ping, Moss, Joel, O’Brien, Kevin J., Nathan, Steven D., Meyer, Keith C., Rosas, Ivan O., Helip-Wooley, Amanda, Huizing, Marjan, Gahl, William A., Gochuico, Bernadette R.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068929/
https://ncbi.nlm.nih.gov/pubmed/24134621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0025OC
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