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Native Small Airways Secrete Bicarbonate

Since the discovery of Cl(−) impermeability in cystic fibrosis (CF) and the cloning of the responsible channel, CF pathology has been widely attributed to a defect in epithelial Cl(−) transport. However, loss of bicarbonate (HCO(3)(−)) transport also plays a major, possibly more critical role in CF...

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Autori principali: Shamsuddin, A. K. M., Quinton, Paul M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068927/
https://ncbi.nlm.nih.gov/pubmed/24224935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0418OC
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