In Silico target fishing: addressing a “Big Data” problem by ligand-based similarity rankings with data fusion

BACKGROUND: Ligand-based in silico target fishing can be used to identify the potential interacting target of bioactive ligands, which is useful for understanding the polypharmacology and safety profile of existing drugs. The underlying principle of the approach is that known bioactive ligands can b...

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Bibliografski detalji
Glavni autori: Liu, Xian, Xu, Yuan, Li, Shanshan, Wang, Yulan, Peng, Jianlong, Luo, Cheng, Luo, Xiaomin, Zheng, Mingyue, Chen, Kaixian, Jiang, Hualiang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068908/
https://ncbi.nlm.nih.gov/pubmed/24976868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-2946-6-33
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