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The mecA Homolog mecC Confers Resistance against β-Lactams in Staphylococcus aureus Irrespective of the Genetic Strain Background

In staphylococci, methicillin resistance is mediated by mecA-encoded penicillin-binding protein 2a (PBP2a), which has a low affinity for beta-lactams. Recently, a novel PBP2a homolog was described as being encoded by mecC, which shares only 70% similarity to mecA. To prove that mecC is the genetic d...

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Hlavní autoři: Ballhausen, Britta, Kriegeskorte, André, Schleimer, Nina, Peters, Georg, Becker, Karsten
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068569/
https://ncbi.nlm.nih.gov/pubmed/24752255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02731-13
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