In Vitro Antifungal Susceptibility of Candida glabrata to Caspofungin and the Presence of FKS Mutations Correlate with Treatment Response in an Immunocompromised Murine Model of Invasive Infection

It has been argued that the in vitro activity of caspofungin (CSP) is not a good predictor of the outcome of echinocandin treatment in vivo. We evaluated the in vitro activity of CSP and the presence of FKS mutations in the hot spot 1 (HS1) region of the FKS1 and FKS2 genes in 17 Candida glabrata st...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Fernández-Silva, Fabiola, Lackner, Michaela, Capilla, Javier, Mayayo, Emilio, Sutton, Deanna, Castanheira, Mariana, Fothergill, Annette W., Lass-Flörl, Cornelia, Guarro, Josep
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068555/
https://ncbi.nlm.nih.gov/pubmed/24733474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02666-13
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker