Screening for Inhibition of Vibrio cholerae VipA-VipB Interaction Identifies Small-Molecule Compounds Active against Type VI Secretion

The type VI secretion system (T6SS) is the most prevalent bacterial secretion system and an important virulence mechanism utilized by Gram-negative bacteria, either to target eukaryotic cells or to combat other microbes. The components show much variability, but some appear essential for the functio...

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Detalhes bibliográficos
Main Authors: Sun, Kun, Bröms, Jeanette, Lavander, Moa, Gurram, Bharat Kumar, Enquist, Per-Anders, Andersson, C. David, Elofsson, Mikael, Sjöstedt, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068513/
https://ncbi.nlm.nih.gov/pubmed/24798289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02819-13
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