In Vitro and In Vivo Activities of Tigecycline-Colistin Combination Therapies against Carbapenem-Resistant Enterobacteriaceae

We assessed the activity of tigecycline (TGC) combined with colistin (COL) against carbapenem-resistant enterobacteria. Synergy occurred in vitro against the majority of isolates, with the exception of Serratia marcescens. In a simple animal model (Galleria mellonella), TGC-COL was superior (P <...

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Autors principals: Betts, Jonathan W., Phee, Lynette M., Hornsey, Michael, Woodford, Neil, Wareham, David W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068506/
https://ncbi.nlm.nih.gov/pubmed/24687491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02449-14
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