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Lipopolysaccharide-Binding Alkylpolyamine DS-96 Inhibits Chlamydia trachomatis Infection by Blocking Attachment and Entry

Vaginally delivered microbicides are being developed to offer women self-initiated protection against transmission of sexually transmitted infections such as Chlamydia trachomatis. A small molecule, DS-96, rationally designed for high affinity to Escherichia coli lipid A, was previously demonstrated...

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Detalles Bibliográficos
Main Authors: Osaka, Ichie, Hefty, P. Scott
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068484/
https://ncbi.nlm.nih.gov/pubmed/24663021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02391-14
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