In Vitro and In Vivo Activities of HPi1, a Selective Antimicrobial against Helicobacter pylori

A high-throughput screen (HTS) was performed to identify molecules specifically active against Helicobacter pylori, the causative agent of peptic ulcer and gastric carcinoma. Currently, treatment of H. pylori infection is suboptimal, with failure rates approaching 25%, despite triple therapy with tw...

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Detalhes bibliográficos
Main Authors: Gavrish, Ekaterina, Shrestha, Binu, Chen, Chao, Lister, Ida, North, E. Jeffrey, Yang, Lei, Lee, Richard E., Han, Angel, Williams, Bronwyn, Charnuska, David, Coleman, Ken, Lewis, Kim, LaFleur, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068456/
https://ncbi.nlm.nih.gov/pubmed/24687512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02573-13
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