Liposome Encapsulation of Ciprofloxacin Improves Protection against Highly Virulent Francisella tularensis Strain Schu S4

Liposome-encapsulated ciprofloxacin for inhalation (CFI) was investigated as a putative postexposure therapeutic for two strains of Francisella tularensis. The efficacies of oral ciprofloxacin and intranasally instilled CFI could not be distinguished in a mouse model of infection with the F. tularen...

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Detalhes bibliográficos
Main Authors: Hamblin, Karleigh A., Armstrong, Stuart J., Barnes, Kay B., Davies, Carwyn, Wong, Jonathan P., Blanchard, James D., Harding, Sarah V., Simpson, Andrew J. H., Atkins, Helen S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068435/
https://ncbi.nlm.nih.gov/pubmed/24637682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02555-13
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