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In-vitro immunosuppression of canine T-lymphocyte-specific proliferation with dexamethasone, cyclosporine, and the active metabolites of azathioprine and leflunomide in a flow-cytometric assay

A high rate of mortality, expense, and complications of immunosuppressive therapy in dogs underscores the need for optimization of drug dosing. The purpose of this study was to determine, using a flow-cytometric assay, the 50% T-cell inhibitory concentration (IC(50)) of dexamethasone, cyclosporine,...

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Detalhes bibliográficos
Main Authors: Nafe, Laura A., Dodam, John R., Reinero, Carol R.
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Veterinary Medical Association 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068407/
https://ncbi.nlm.nih.gov/pubmed/24982547
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