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Vital functions of the malarial ookinete protein CTRP reside in the A domains

The transformation of malaria ookinetes into oocysts occurs in the mosquito midgut and is a major bottleneck for parasite transmission. The secreted ookinete surface protein CTRP (circumsporozoite- and TRAP-related protein) is essential for this transition, and hence constitutes a potential target f...

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Bibliographic Details
Main Authors: Ramakrishnan, Chandra, Dessens, Johannes T., Armson, Rebecca, Pinto, Sofia B., Talman, Arthur M., Blagborough, Andrew M., Sinden, Robert E.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068204/
https://ncbi.nlm.nih.gov/pubmed/21729699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2011.05.007
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