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Systems biology approaches to understanding Epithelial Mesenchymal Transition (EMT) in mucosal remodeling and signaling in asthma

A pathological hallmark of asthma is chronic injury and repair, producing dysfunction of the epithelial barrier function. In this setting, increased oxidative stress, growth factor- and cytokine stimulation, together with extracellular matrix contact produces transcriptional reprogramming of the epi...

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Détails bibliographiques
Auteurs principaux: Ijaz, Talha, Pazdrak, Konrad, Kalita, Mridul, Konig, Rolf, Choudhary, Sanjeev, Tian, Bing, Boldogh, Istvan, Brasier, Allan R
Format: Artigo
Langue:Inglês
Publié: World Allergy Organization 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068075/
https://ncbi.nlm.nih.gov/pubmed/24982697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1939-4551-7-13
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