Ion Mobility Mass Spectrometry of a Rotary ATPase Reveals ATP-induced Reduction in Conformational Flexibility

Rotary ATPases play fundamental roles in energy conversion, their catalytic rotation being associated with inter-domain fluctuations and heterogeneity of conformational states. Using ion mobility mass spectrometry (IM-MS) we compare the conformational dynamics of the intact ATPase from Thermus therm...

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Autores principales: Zhou, Min, Politis, Argyris, Davies, Roberta, Liko, Idlir, Wu, Kuan-Jung, Stewart, Alastair G., Stock, Daniela, Robinson, Carol V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067995/
https://ncbi.nlm.nih.gov/pubmed/24557135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1868
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