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Writers and Readers of Histone Acetylation: Structure, Mechanism, and Inhibition

Histone acetylation marks are written by histone acetyltransferases (HATs) and read by bromodomains (BrDs), and less commonly by other protein modules. These proteins regulate many transcription-mediated biological processes, and their aberrant activities are correlated with several human diseases....

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Detalhes bibliográficos
Main Authors: Marmorstein, Ronen, Zhou, Ming-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067988/
https://ncbi.nlm.nih.gov/pubmed/24984779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a018762
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