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Writers and Readers of Histone Acetylation: Structure, Mechanism, and Inhibition
Histone acetylation marks are written by histone acetyltransferases (HATs) and read by bromodomains (BrDs), and less commonly by other protein modules. These proteins regulate many transcription-mediated biological processes, and their aberrant activities are correlated with several human diseases....
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4067988/ https://ncbi.nlm.nih.gov/pubmed/24984779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a018762 |
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