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Progesterone protects normative anxiety-like responding among ovariectomized female mice that conditionally express the HIV-1 regulatory protein, Tat, in the CNS

Increased anxiety is co-morbid with human immunodeficiency virus (HIV) infection. Actions of the neurotoxic HIV-1 regulatory protein, Tat, may contribute to affective dysfunction. We hypothesized that Tat expression would increase anxiety-like behavior of female GT-tg bigenic mice that express HIV-1...

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Autores principales: Paris, Jason J., Fenwick, Jason, McLaughlin, Jay P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067900/
https://ncbi.nlm.nih.gov/pubmed/24726788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yhbeh.2014.04.001
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