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Imaging the fate of histone Cse4 reveals de novo replacement in S phase and subsequent stable residence at centromeres

The budding yeast centromere contains Cse4, a specialized histone H3 variant. Fluorescence pulse-chase analysis of an internally tagged Cse4 reveals that it is replaced with newly synthesized molecules in S phase, remaining stably associated with centromeres thereafter. In contrast, C-terminally-tag...

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Hlavní autoři: Wisniewski, Jan, Hajj, Bassam, Chen, Jiji, Mizuguchi, Gaku, Xiao, Hua, Wei, Debbie, Dahan, Maxime, Wu, Carl
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067749/
https://ncbi.nlm.nih.gov/pubmed/24844245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02203
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